Hypogravitational Osteoporosis :: essays research papers

Osteoporosis acondition characterized by an absolute decrease inthe amount of bone present to a level below whichit is capable of keep an eye oning the structural integrityof the skeleton. To state the obvious, valetbeings have evolved under Earths gravity "1G".Our musculoskeleton musical arrangement have developed to inspection and repair us navigate in this gravitational field, endowedwith ability to fit as needed under variousstress, strains and available energy requirement.The transcription consists of Bone a highly specializedand dynamic supporting interweave which provides thevertebrates its smashed infrastructure. It consists ofspecialized connective tissue cells c whollyedosteocytes and a matrix consisting of ingrainedfibers held together by an organic cement whichgives bone its tenacity, elasticity and its resilience.It likewise has an inorganic component located in thecement between the fibers consisting of calciumphosphate 85% Calcium carbonate 10% others 5% which give it the hardness and rigidity.Other than providing the rigid infrastructure, itprotects vital organs like the brain, serves as acomplex prize system, acts as a storage area forcalcium which is vital for man metabolism,houses the bone marrow within its mid cavity andto top it all it is capable of changing its architectureand kettle of fish in response to outdoor(a) and inner stress.It is this dynamic remodeling of bone which is ofprimary interest in microgravity. To bump the impactof this dynamicity it should be noted that a boneremodeling unit a linked phenomena of bonereabsorption and bone formation is initiated andanother finished about both ten seconds in ahealthy adult. This dynamic system suffices to windup(prenominal) stress or lack of it by increasing thebone mass/ dumbness or decreasing it as per thedemand on the system. -eg a person dealing withincreased robotlike stress will respond withincreased mass / density of the bone and a personwho leads a sed entary life will have decreasedmass/density of bone but the right amount tosupport his structure against the mechanicalstresses she/she exists in. Hormones also play amajor role as seen in postmenopausal femalesosteoporosis (lack of estrogens) in which the rateof bone reformation is usually conventionalism with the rateof bone re-absorption increased. In Skeletalsystem whose mass introduce a dynamichomeostasis in 1g incubus- bearing,when placed inmicrogravity for any extensive period of timerequiring practically no weight bearing, theregulatory system of bone/calcium reacts bydecreasing its mass. After all, why take away all thatextra mass and use all that energy to maintain whatis not needed? Logically the greatest loss-demineralization- occurs in the weight bearingbones of the leg Os Calcis and spine. Bone losshas been estimated by calcium-balance studiesand body waste studies. An increased urinary